Statistical Problems in Medicine and Biology G48.2313 Prerequisite: advanced courses in biostatistics or statistics. Permission of the instructor. Goldberg and faculty. 4 points. (Wed. afternoons) In this course, students will participate in the clinical and translational research process with investigators conducting research in a wide variety of areas in medicine and biology. These areas range from clinical trials in cancer, cardiovascular disease, etc. to comparisons of gene expression profiles resulting from different exposures to potential carcinogens in animals or people. Researchers will present their problems and the students will develop their skills to : . develop solutions that include appropriate study designs and statistical considerations . collaborate in the development of research proposals . collaborate in the planning of the statistical analysis for a research project . conduct appropriate statistical analysis for a research project in collaboration with an investigator . prepare a report for a research project in collaboration with an investigator. Students will be exposed to realistic statistical and scientific problems as well as the statistical approaches for solving these problems. This course will develop experience and skills in statistical collaboration. Researchers will present their problems in class sessions (every other week) and students will present their solutions to the class and faculty in alternate weeks.