Blaser Lab

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Members of Martin J. Blaser Lab


Dr. Guillermo Perez Perez

 

Dr. Guillermo Perez Perez, Prinicpal Investigator

Associate Professor of Medicine & Microbiology

CURRENT RESEARCH INTERESTS:
The Microbiology, Pathogenesis and Epidemiology of Bacterial Enteric Diseases

My major interest is in bacterial infections that continue to be a major public health problem around the world. The major areas of research in our laboratory include the microbiology, pathogenesis and epidemiology of bacterial enteric diseases.

Our current research focuses on the study of the gram negative bacteria Helicobacter pylori and Campylobacter jejuni. H. pylori is among the most common bacteria that colonize humans. Nearly 50% of the world1s adult population carries this organism. Our interest is toward the characterization of the human immune response to major H. pylori antigens, and to understand the role of virulence factors of H. pylori associated with different clinical outcomes (including peptic ulcer disease and gastric neoplasia). In that regard, we also are working to understand the nature of the association of H. pylori with gastric carcinoma.

Another area of interest in our current studies is to determine how H. pylori is acquired and to describe the early stages of the natural history of the colonization of children. These studies combine epidemiologic approaches with clinical and basic immunology, as well as using molecular probes and amplification techniques for analysis.

Education/Training:

I got my D.Sc. degree in Mexico city in June 1985, and my M.C. degree in August 1982. I was appointed to NYU School of Medicine in July 2000.

   

Selected Publications:

1. Blaser, MJ; Nomura, A; Lee, J; Stemmerman, GN; Perez-Perez, GI. "Early-life family structure and microbially induced cancer risk". PLoS medicine. 2007; 4: 53 (#J0123938)
2. Kamangar, F; Qiao, YL; Blaser, MJ; Sun, XD; Katki, H; Fan, JH; Perez-Perez, GI; Abnet, CC; Zhao, P; D Mark, S; Taylor, PR; Dawsey, SM. "Helicobacter pylori and oesophageal and gastric cancers in a prospective study in China". British journal of cancer. 2007; 96: 172 (#J0123312)
3. Bik EM; Eckburg PB; Gill SR; Nelson KE; Purdom EA; Francois F; Perez-Perez G; Blaser MJ; Relman DA. "Molecular analysis of the bacterial microbiota in the human stomach". Proceedings of the National Academy of Sciences of the United States of America. 2006; 103: 732 (#J0111407)
4. Cho A; Chaudhry A; Minsky-Primus L; Tso A; Perez-Perez G; Diehl DL; Marcus SG; Gany FM. "Follow-up care after a diagnosis of Helicobacter pylori infection in an Asian immigrant cohort". Journal of clinical gastroenterology. 2006; 40: 29 (#J0110663)
5. Cho, Alex; Chaudhry, Amina; Minsky-Primus, Lisa; Tso, Alan; Perez-Perez, Guillermo; Diehl, David; Marcus, Stuart G; Gany, Francesca M. "Acceptance of repeat esophagogastroduodenoscopy to detect gastric cancer in a chinese immigrant cohort". Journal of clinical gastroenterology. 2006; 40: 606 (#J0120352)
6. Goldman, C; Barrado, A; Janjetic, M; Balcarce, N; Rua, EC; Oshiro, M; Calcagno, ML; Sarrasague, MM; Fuda, J; Weill, R; Zubillaga, M; Perez-Perez, GI; Boccio, J. "Factors associated with H pylori epidemiology in symptomatic children in Buenos Aires, Argentina". World journal of gastroenterology : WJG. 2006; 12: 5384 (#J0120697)
7. Kamangar, F; Dawsey, SM; Blaser, MJ; Perez-Perez, GI; Pietinen, P; Newschaffer, CJ; Abnet, CC; Albanes, D; Virtamo, J; Taylor, PR. "Opposing risks of gastric cardia and noncardia gastric adenocarcinomas associated with Helicobacter pylori seropositivity". Journal of the National Cancer Institute. 2006; 98: 1445 (#J0121752)
8. Marcano-Lozada, MJ; Urrestarazu, MI; Serrano, NM; Perez-Perez, GI. "Association of Helicobacter pylori and chronic idiopathic urticaria [Abstract]". Helicobacter. 2006; 11: 369 (#J0120592)
9. Moreno-Gutierrez, FJ; Garza-Gonzalez, E; Bosques-Padilla, FJ; Perez-Perez, GI. "In vivo and in vitro expression of the TLR-4 and TLR-5 receptors during Helicobacter pylori infection [Abstract]". Helicobacter. 2006; 11: 349 (#J0120591)
10. Olivares A; Buadze M; Kutubidze T; Lobjanidze M; Labauri L; Kutubidze R; Chikviladze D; Zhvania M; Kharzeishvili O; Lomidze N; Perez-Perez GI. "Prevalence of Helicobacter pylori in Georgian patients with dyspepsia". Helicobacter. 2006; 11: 81 (#J0114416)
11. Perez-Perez, GI; Chao, L; Minhong, C; Andersson, M; Olivares, AZ. "Differences in the 3 ' cagA region between Helicobacter pylori strains of East Asian and African origin [Abstract]". Helicobacter. 2006; 11: 343 (#J0120590)
12. Perez-Perez, GI; Andersson, M; Olivares, AZ; Gonzalez, EG; Padilla, FB; Torres, J; Blaser, MJ. "Specific geographic genotypes among Helicobacter pylori strains [Abstract]". Helicobacter. 2006; 11: 342 (#J0120589)
13. Perez-Perez, GI; Wong, C; Olivares, AZ; Gonzalez, EG; Padilla, FB; Blaser, MJ. "Stability and variability of cagA and its correlation with disease outcome [Abstract]". Helicobacter. 2006; 11: 333 (#J0120588)
14. Perry, S; Sanchez, MDL; Yang, SF; Haggerty, TD; Hurst, P; Perez-Perez, G; Parsonnet, J. "Gastroenteritis and transmission of Helicobacter pylori infection in households". Emerging infectious diseases. 2006; 12: 1701 (#J0121647)
15. Portal-Celhay C; Perez-Perez GI. "Immune responses to Helicobacter pylori colonization: mechanisms and clinical outcomes". Clinical science (London, 1979). 2006; 110: 305 (#J0114417)
16. Vidal, T; Gutierrez, B; Valmana, CE; Ochoa, R; Megraud, F; Perez-Perez, GI; Paniagua, M; Mendz, GL. "Helicobacter pylori infection diagnosis in gastroduodenal disease in La Habana, Cuba [Abstract]". Helicobacter. 2006; 11: 384 (#J0120593)
17. Zuniga-Noriega JR; Bosques-Padilla FJ; Perez-Perez GI; Tijerina-Menchaca R; Flores-Gutierrez JP; Maldonado Garza HJ; Garza-Gonzalez E. "Diagnostic utility of invasive tests and serology for the diagnosis of Helicobacter pylori infection in different clinical presentations". Archives of medical research (Mexico). 2006; 37: 123 (#J0114419)
18. Alpizar-Alpizar W; Perez-Perez GI; Une C; Cuenca P; Sierra R. "Association of interleukin-1B and interleukin-1RN polymorphisms with gastric cancer in a high-risk population of Costa Rica". Clinical & experimental medicine. 2005; 5: 169 (#J0114418)
19. Bhat N; Gaensbauer J; Peek RM; Bloch K; Tham K-T; Blaser MJ; Perez-Perez G. "Local and systemic immune and inflammatory responses to Helicobacter pylori strains". Clinical & diagnostic laboratory immunology. 2005; 12: 1393 (#J0110434)
20. Cooperberg BA; Bini EJ; Cohen H; Olivares AZ; Dacoll C; Perez-Perez GI. "Preliminary report of the prevalence of Helicobacter pylori and distribution of vacA genotypes in Montevideo, Uruguay". Revista Brasileira de Medicina. 2005; 62: 290 (#J0105901)
21. Franco AT; Israel DA; Washington MK; Krishna U; Fox JG; Rogers AB; Neish AS; Collier-Hyams L; Perez-Perez GI; Hatakeyama M; Whitehead R; Gaus K; O'Brien DP; Romero-Gallo J; Peek RM Jr. "Activation of beta-catenin by carcinogenic Helicobacter pylori". Proceedings of the National Academy of Sciences of the United States of America. 2005; 102: 10646 (#J0114420)
22. Garza-Gonzalez, E; Bosques-Padilla, FJ; El-Omar, E; Hold, G; Tijerina-Menchaca, R; Maldonado-Garza, HJ; Perez-Perez, GI. "Role of the polymorphic IL-1B, IL-1RN and TNF-A genes in distal gastric cancer in Mexico". International journal of cancer. 2005; 114: 237 (#J0076972)
23. Ghose C; Perez-Perez GI; van Doorn LJ; Dominguez-Bello MG; Blaser MJ. "High Frequency of Gastric Colonization with Multiple Helicobacter pylori Strains in Venezuelan Subjects". Journal of clinical microbiology. 2005; 43: 2635 (#J0102946)
24. Haggerty, TD; Perry, S; Sanchez, L; Perez-Perez, G; Parsonnet, J. "Significance of transiently positive enzyme-linked immunosorbent assay results in detection of Helicobacter pylori in stool samples from children". Journal of clinical microbiology. 2005; 43: 2220 (#J0102677)
25. Nomura AM; Kolonel LN; Miki K; Stemmermann GN; Wilkens LR; Goodman MT; Perez-Perez GI; Blaser MJ. "Helicobacter pylori, pepsinogen, and gastric adenocarcinoma in Hawaii". Journal of infectious diseases. 2005; 191: 2075 (#J0114421)
26. Perez-Perez GI; Bosques-Padilla FJ; Crosatti ML; Tijerina-Menchaca R; Garza-Gonzalez E. "Role of p53 codon 72 polymorphism in the risk of development of distal gastric cancer". Scandinavian journal of gastroenterology. 2005; 40: 56 (#J0096410)
27. Perez-Perez GI; Olivares AZ; Foo FY; Foo S; Neusy AJ; Ng C; Holzman RS; Marmor M; Blaser MJ. "Seroprevalence of Helicobacter pylori in New York City populations originating in East Asia". Journal of urban health. 2005; 82: 510 (#J0106207)
28. Aspholm-Hurtig M; Dailide G; Lahmann M; Kalia A; Ilver D; Roche N; Vikstrom S; Sjostrom R; Linden S; Backstrom A; Lundberg C; Arnqvist A; Mahdavi J; Nilsson UJ; Velapatino B; Gilman RH; Gerhard M; Alarcon T; Lopez-Brea M; Nakazawa T; Fox JG; Correa P; Dominguez-Bello MG; Perez-Perez GI; Blaser MJ; Normark S; Carlstedt I; Oscarson S; Teneberg S; Berg DE; Boren T. "Functional Adaptation of BabA, the H. pylori ABO Blood Group Antigen Binding Adhesin". Science. 2004; 305: 519 (#J0068176)
29. Duck WM; Sobel J; Pruckler JM; Song Q; Swerdlow D; Friedman C; Sulka A; Swaminathan B; Taylor T; Hoekstra M; Griffin P; Smoot D; Peek R; Metz DC; Bloom PB; Goldschmidt S; Parsonnet J; Triadafilopoulos G; Perez-Perez GI; Vakil N; Ernst P; Czinn S; Dunne D; Gold BD. "Antimicrobial resistance incidence and risk factors among Helicobacter pylori-infected persons, United States". Emerging infectious diseases. 2004; 10: 1088 (#J0069621)
30. Eamranond PP; Torres J; Munoz O; Perez-Perez GI. "Age-Specific Immune Response to HspA in Helicobacter pylori-Positive Persons in Mexico". Clinical & diagnostic laboratory immunology. 2004; 11: 983 (#J0069619)
31. Garza-Gonzalez E; Bosques-Padilla FJ; Perez-Perez GI; Flores-Gutierrez JP; Tijerina-Menchaca R. "Association of gastric cancer, HLA-DQA1, and infection with Helicobacter pylori CagA+ and VacA+ in a Mexican population". Journal of gastroenterology. 2004; 39: 1138 (#J0114423)
32. Garza-Gonzalez E; Tijerina-Menchaca R; Perez-Perez GI; Bosques-Padilla FJ. "Bacteriostatic and bactericidal activity of rabeprazole against Helicobacter pylori [letter]". Journal of chemotherapy. 2004; 16: 612 (#J0114422)
33. Garza-Gonzalez E; Bosques-Padilla FJ; Tijerina-Menchaca R; Perez-Perez GI. "Characterisation of Helicobacter pylori isolates from the north-eastern region of Mexico". Clinical microbiology & infection. 2004; 10: 41 (#J0069624)
34. Perez-Perez GI; Rothenbacher D; Brenner H. "Epidemiology of Helicobacter pylori Infection". Helicobacter. 2004; 9 Suppl 1: 1 (#J0069620)
35. Aras RA; Fischer W; Perez-Perez GI; Crosatti M; Ando T; Haas R; Blaser MJ. "Plasticity of repetitive DNA sequences within a bacterial (Type IV) secretion system component". Journal of experimental medicine. 2003; 198: 1349 (#J0067223)
36. Belongia EA; Chyou PH; Greenlee RT; Perez-Perez G; Bibb WF; DeVries EO. "Diarrhea Incidence and Farm-Related Risk Factors for Escherichia coli O157:H7 and Campylobacter jejuni Antibodies among Rural Children". Journal of infectious diseases. 2003; 187: 1460 (#J0047793)
37. Bosques-Padilla FJ; Tijerina-Menchaca R; Perez-Perez GI; Flores-Gutierrez JP; Garza-Gonzalez E. "Comparison of Helicobacter pylori Prevalence in Symptomatic Patients in Northeastern Mexico with the Rest of the Country. Its Association with Gastrointestinal Disease". Archives of medical research (Mexico). 2003; 34: 60 (#J0047796)
38. Falush D; Wirth T; Linz B; Pritchard JK; Stephens M; Kidd M; Blaser MJ; Graham DY; Vacher S; Perez-Perez GI; Yamaoka Y; Megraud F; Otto K; Reichard U; Katzowitsch E; Wang X; Achtman M; Suerbaum S. "Traces of human migrations in Helicobacter pylori populations". Science. 2003; 299: 1582 (#J0047746)
39. Garza-Gonzalez E; Hold G; Perez-Perez GI; Bosques-Padilla FJ; Tijerina-Menchaca R; Maldonado-Garza HJ; el-Omar E. "[Role of polymorphism of certain cytokines in gastric cancer in Mexico. Preliminary results]". Revista de gastroenterologia de Mexico. 2003; 68: 107 (#J0069622)
40. Garza-Gonzalez E; Bosques-Padilla FJ; Tijerina-Menchaca R; Flores-Gutierrez JP; Maldonado-Garza HJ; Perez-Perez GI. "Comparision of endoscopy-based and serum-based methods for the diagnosis of Helicobacter pylori". Canadian journal of gastroenterology. 2003; 17: 101 (#J0047795)
41. Perez-Perez GI; Sack RB; Reid R; Santosham M; Croll J; Blaser MJ. "Transient and persistent Helicobacter pylori colonization in Native American children". Journal of clinical microbiology. 2003; 41: 2401 (#J0053239)
42. Simon JA; Hudes ES; Perez-Perez GI. "Relation of serum ascorbic acid to Helicobacter pylori serology in US adults: the Third National Health and Nutrition Examination Survey". Journal of the American College of Nutrition. 2003; 22: 283 (#J0069625)
43. Camorlinga, MP; Celis-Cruz, C; Romero, J; Ortiz, M; Lopez-Corella, E; Perez-Perez, G; Coria-Jimenez, R. "Simultaneous experimental colonization of Eriones unguiculatus (Mongolian gerbil) with PAI+ and PAI- Helicobacter pylori strains [Abstract]". Gut: journal of the British Society of Gastroenterology. 2002; 51: A49 (#J0102371)
44. Everhart JE; Kruszon-Moran D; Perez-Perez G. "Reliability of Helicobacter pylori and CagA serological assays". Clinical & diagnostic laboratory immunology. 2002; 9: 412 (#J0047798)
45. Freedman A; Afonja O; Chang MW; Mostashari F; Blaser M; Perez-Perez G; Lazarus H; Schacht R; Guttenberg J; Traister M; Borkowsky W. "Cutaneous anthrax associated with microangiopathic hemolytic anemia and coagulopathy in a 7-month-old infant". JAMA. 2002; 287: 869 (#J0028237)
46. Garza-Gonzalez E; Perez-Perez GI; Tijerina-Menchaca R; Maldonado-Garza HJ; Bosques-Padilla FJ. "[Helicobacter pylori genotypes and their association with host's immune response]". Revista de gastroenterologia de Mexico. 2002; 67: 155 (#J0047794)
47. Garza-Gonzalez E; Perez-Perez GI; Alanis-Aguilar O; Tijerina-Menchaca R; Maldonado-Garza HJ; Bosques-Padilla FJ. "Antibiotic susceptibility patterns of Helicobacter pylori strains isolated from northeastern Mexico". Journal of chemotherapy. 2002; 14: 342 (#J0047797)
48. Garza-Gonzalez, E; Bosques-Padilla, FJ; Perez-Perez, GI; Tijerina-Menchaca, R. "Potential correlation of HLA-DQ alleles and clinical outcomes related to H-pylori CagA plus and VacA [Abstract]". Gut: journal of the British Society of Gastroenterology. 2002; 51: A25 (#J0102370)
49. Garza-Gonzalez, E; Hold, GL; Perez-Perez, GI; Bosques-Padilla, FJ; Tijerina-Menchaca, R; El-Omar, EM. "Role of the polymorphic cytokines genes in gastric cancer in Mexico [Abstract]". Gut: journal of the British Society of Gastroenterology. 2002; 51: A23 (#J0102369)
50. Ghose C; Perez-Perez GI; Dominguez-Bello MG; Pride DT; Bravi CM; Blaser MJ. "East Asian genotypes of Helicobacter pylori strains in Amerindians provide evidence for its ancient human carriage". Proceedings of the National Academy of Sciences of the United States of America. 2002; 99: 15107 (#J0047753)
51. Groves FD; Perez-Perez G; Zhang L; You WC; Lipsitz SR; Gail MH; Fraumeni JF Jr; Blaser MJ. "Serum antibodies to Helicobacter pylori and the CagA antigen do not explain differences in the prevalence of precancerous gastric lesions in two Chinese populations with contrasting gastric cancer rates". Cancer epidemiology biomarkers & prevention. 2002; 11: 1091 (#J0047758)
52. Levine SM; Perez-Perez G; Olivares A; Yee H; Hanna BA; Blaser MJ. "PCR-based detection of Bacillus anthracis in formalin-fixed tissue from a patient receiving ciprofloxacin". Journal of clinical microbiology. 2002; 40: 4360 (#J0047755)
53. Limburg PJ; Stolzenberg-Solomon RZ; Colbert LH; Perez-Perez GI; Blaser MJ; Taylor PR; Virtamo J; Albanes D. "Helicobacter pylori seropositivity and colorectal cancer risk: a prospective study of male smokers". Cancer epidemiology biomarkers & prevention. 2002; 11: 1095 (#J0047757)
54. Nomura AM; Lee J; Stemmermann GN; Nomura RY; Perez-Perez GI; Blaser MJ. "Helicobacter pylori CagA seropositivity and gastric carcinoma risk in a Japanese American population". Journal of infectious diseases. 2002; 186: 1138 (#J0047759)
55. Nomura AM; Perez-Perez GI; Lee J; Stemmermann G; Blaser MJ. "Relation between Helicobacter pylori cagA status and risk of peptic ulcer disease". American journal of epidemiology. 2002; 155: 1054 (#J0047763)
56. Perez-Perez, GI; Olivares, AZ; Peek, RM; Tham, K; Blaser, MJ. "Detection of Helicobacter pylori in gastric juice by PCR [Abstract]". Gut: journal of the British Society of Gastroenterology. 2002; 51: A110 (#J0102372)
57. Perez-Perez GI; Salomaa A; Kosunen TU; Daverman B; Rautelin H; Aromaa A; Knekt P; Blaser MJ. "Evidence that cagA(+) Helicobacter pylori strains are disappearing more rapidly than cagA(-) strains". Gut: journal of the British Society of Gastroenterology. 2002; 50: 295 (#J0027810)
58. Romero-Gallo J; Perez-Perez GI; Novick RP; Kamath P; Norbu T; Blaser MJ. "Responses of endoscopy patients in Ladakh, India, to Helicobacter pylori whole-cell and Cag A antigens". Clinical & diagnostic laboratory immunology. 2002; 9: 1313 (#J0047754)
59. Tijerina-Menchaca R; Bosques-Padilla FJ; Perez-Perez GI; Maldonado-Garza HJ; Garza-Gonzalez E. "Validacion del Western blot para la deteccion del genotipo de Helicobacter pylori". Medicina universitaria. 2002; 4: 212 (#J0052257)
60. Torres J; Camorlinga-Ponce M; Perez-Perez G; Munoz L; Munoz O. "Specific serum immunoglobulin G response to urease and CagA antigens of Helicobacter pylori in infected children and adults in a country with high prevalence of infection". Clinical & diagnostic laboratory immunology. 2002; 9: 97 (#J0047799)
61. Dominguez-Bello, MG; Godette, G; Sundseth, R; Perez-Perez, GI; Wojciechowski, M; Bonaventura, C; Henkens, R. "Quantitative molecular electrochemical detection of Helicobacter pylori [Abstract]". Gut: journal of the British Society of Gastroenterology. 2001; 49: A99 (#J0099194)
62. Dominguez-Bello, MG; Perez-Perez, GI; Pacheco, N; Gonzalez, E; Garza-Gonzalez, E; Mora, R; Mago, V; Gomez, I. "Seroprevalence of Helicobacter pylori and CagA in areas of Venezuela with different gastric cancer risks [Abstract]". Gut: journal of the British Society of Gastroenterology. 2001; 49: A36 (#J0099193)
63. Figueiredo C; Quint W; Nouhan N; van Den Munckhof H; Herbrink P; Scherpenisse J; de Boer W; Schneeberger P; Perez-Perez G; Blaser MJ; van Doorn LJ. "Assessment of Helicobacter pylori vacA and cagA Genotypes and Host Serological Response". Journal of clinical microbiology. 2001; 39: 1339 (#J0020873)
64. Garza-Gonzalez, E; Bosques-Padilla, FJ; Maldonado-Garza, H; Tijerina-Menchaca, R; Perez-Perez, GI. "Characterization of Helicobacter pylori strains isolated from the northeast region of Mexico [Abstract]". Gut: journal of the British Society of Gastroenterology. 2001; 49: A34 (#J0099192)
65. Ghose, C; Perez-Perez, GI; Dominguez-Bello, MG; Blaser, MJ. "Helicobacter pylori among indigenous peoples of Venezuela: European or Asian origin? [Abstract]". Clinical infectious diseases. 2001; 33: 1233 (#J0099162)
66. Limburg P; Qiao Y; Mark S; Wang G; Perez-Perez G; Blaser M; Wu Y; Zou X; Dong Z; Taylor P; Dawsey S. "Helicobacter pylori seropositivity and subsite-specific gastric cancer risks in Linxian, China". Journal of the National Cancer Institute. 2001; 93: 226 (#J0047804)
67. Moss SF; Sordillo EM; Abdalla AM; Makarov V; Hanzely Z; Perez-Perez GI; Blaser MJ; Holt PR. "Increased gastric epithelial cell apoptosis associated with colonization with cagA + Helicobacter pylori strains". Cancer research. 2001; 61: 1406 (#J0020876)
68. Munoz L; Gonzalez-Valencia G; Perez-Perez GI; Giono-Cerezo S; Munoz O; Torres J. "A comparison of Lewis x and Lewis y expression in Helicobacter pylori obtained from children and adults". Journal of infectious diseases. 2001; 183: 1147 (#J0027813)
69. Perez-Perez, GI; Garza-Gonzalez, E; Flores-Gutierrez, JP; Maldonado-Garza, HJ; Bosques-Padilla, FJ; Tijerina-Menchaca, R. "Comparison of invasive and serological tests for the diagnostic of Helicobacter pylori [Abstract]". Gut: journal of the British Society of Gastroenterology. 2001; 49: A104 (#J0099195)
70. Perez-Perez, GI; Dominguez-Bello, MG; Ghose, C; Pacheco, N; Gonzalez, E; Mago, V; de Novoa, PG; Gomez, I; Mora, R; Blaser, MJ. "Presence of specific Asian Helicobacter pylori genotypes in Amerindians in Venezuela [Abstract]". Gut: journal of the British Society of Gastroenterology. 2001; 49: A33 (#J0099191)
71. Stolzenberg-Solomon RZ; Blaser MJ; Limburg PJ; Perez-Perez G; Taylor PR; Virtamo J; Albanes D. "Helicobacter pylori seropositivity as a risk factor for pancreatic cancer". Journal of the National Cancer Institute. 2001; 93: 937 (#J0047801)
72. Tham KT; Peek RM; Atherton JC; Cover TL; Perez-Perez GI; Shyr Y; Blaser MJ. "Helicobacter pylori genotypes, host factors, and gastric mucosal histopathology in peptic ulcer disease". Human pathology. 2001; 32: 264 (#J0020874)
73. Torres J; Camorlinga-Ponce M; Perez-Perez G; Madrazo-De la Garza A; Dehesa M; Gonzalez-Valencia G; Munoz O. "Increasing multidrug resistance in Helicobacter pylori strains isolated from children and adults in Mexico". Journal of clinical microbiology. 2001; 39: 2677 (#J0047800)
74. Torres J; Camorlinga M; Perez-Perez G; Gonzalez G; Munoz O. "Validation of the string test for the recovery of Helicobacter pylori from gastric secretions and correlation of its results with urea breath test results, serology, and gastric pH levels". Journal of clinical microbiology. 2001; 39: 1650 (#J0047802)
75. You WC; Zhang L; Pan KF; Jiang J; Chang YS; Perez-Perez GI; Liu WD; MA JL; Gail MH; Blaser MJ; Fraumeni JF; Xu GW. "Helicobacter pylori prevalence and CagA status among children in two counties of China with high and low risks of gastric cancer". Annales of epidemiology. 2001; 11: 543 (#J0027811)
76. Ando T; Perez-Perez GI; Kusugami K; Ohsuga M; Bloch KC; Blaser MJ. "Anti-CagA immunoglobulin G responses correlate with interleukin-8 induction in human gastric mucosal biopsy culture". Clinical & diagnostic laboratory immunology. 2000; 7: 803 (#J0020888)
77. Everhart JE; Kruszon-Moran D; Perez-Perez GI; Tralka TS; McQuillan G. "Seroprevalence and ethnic differences in Helicobacter pylori infection among adults in the United States". Journal of infectious diseases. 2000; 181: 1359 (#J0027815)
78. Haley, CA; D'Agata, EM; Perez-Perez, GI; Blaser, MJ; McGowan, CC. "Association between H-pylori seropositivity and atrophic Gastritis in HIV-infected persons [Abstract]". Clinical infectious diseases. 2000; 31: 234 (#J0097649)
79. Harford WV; Barnett C; Lee E; Perez-Perez G; Blaser MJ; Peterson WL. "Acute gastritis with hypochlorhydria: report of 35 cases with long term follow up". Gut: journal of the British Society of Gastroenterology. 2000; 47: 467 (#J0020887)
80. Keenan J; Day T; Neal S; Cook B; Perez-Perez G; Allardyce R; Bagshaw P. "A role for the bacterial outer membrane in the pathogenesis of Helicobacter pylori infection". FEMS microbiology letters. 2000; 182: 259 (#J0047808)
81. Legath, AJ; Perez-Perez, GI; Rautelin, H; Kosunen, TU; Blaser, MJ. "Long term stability of serum IgG1/IgG2 antibody ratios to Helicobacter pylori in healthy adults [Abstract]". Clinical infectious diseases. 2000; 31: 233 (#J0097648)
82. Legath, AJ; Perez-Perez, GI; Rautelin, H; Kosunen, TU; Peek, RM; Sack, RB; Blaser, MJ. "Serum IgG recognition of Helicobacter pylori antigens after acute acquisition or persistent carriage of the organism [Abstract]". Clinical infectious diseases. 2000; 31: 233 (#J0097647)
83. Loffeld RJ; Werdmuller BF; Kuster JG; Perez-Perez GI; Blaser MJ; Kuipers EJ. "Colonization with cagA-positive Helicobacter pylori strains inversely associated with reflux esophagitis and Barrett's esophagus". Digestion. 2000; 62: 95 (#J0020881)
84. Mao HV; Lak BV; Long T; Chung NQ; Thang DM; Hop TV; Chien NN; Hoan PQ; Henley KS; Perez-Perez GI; Connor BA; Stone CD; Chey WD. "Omeprazole or ranitidine bismuth citrate triple therapy to treat Helicobacter pylori infection: a randomized, controlled trial in Vietnamese patients with duodenal ulcer". Alimentary pharmacology & therapeutics. 2000; 14: 97 (#J0027817)
85. Perez-Perez GI. "[Is the association of Helicobacter pylori with humans a classical example of parasitism?]". Revista de gastroenterologia de Mexico. 2000; 65: 7 (#J0027812)
86. Perez-Perez GI. "Accurate diagnosis of Helicobacter pylori. Culture, including transport". Gastroenterology clinics of North America. 2000; 29: 879 (#J0023215)
87. Perez-Perez, GI; Legath, AJ; Rautelin, H; Kosunen, TU; Blaser, MJ. "Long-term stability of serum IgG1/IgG2 antibody ratios to Helicobacter pylori in healthy adults [Abstract]". Gut: journal of the British Society of Gastroenterology. 2000; 47: A35 (#J0097444)
88. Perez-Perez GI; Israel DA. "Role of iron in Helicobacter pylori: its influence in outer membrane protein expression and in pathogenicity". European journal of gastroenterology & hepatology. 2000; 12: 1263 (#J0027814)
89. Riveron AM; Lopez-Canovas L; Flores E; Perez-Perez G; Luna-Arias JP; Orozco E. "Algorithm to predict MiniCHEF electrophoresis patterns of Entamoeba histolytica DNA". Archives of medical research (Mexico). 2000; 31: S279 (#J0047805)
90. Riveron AM; Lopez-Canovas L; Baez-Camargo M; Flores E; Perez-Perez G; Luna-Arias JP; Orozco E. "Circular and linear DNA molecules in the Entamoeba histolytica complex molecular karyotype". European biophysics journal. 2000; 29: 48 (#J0047807)
91. Torres J; Perez-Perez G; Goodman KJ; Atherton JC; Gold BD; Harris PR; la Garza AM; Guarner J; Munoz O. "A comprehensive review of the natural history of Helicobacter pylori infection in children". Archives of medical research (Mexico). 2000; 31: 431 (#J0047803)
92. Vaezi MF; Falk GW; Peek RM; Vicari JJ; Goldblum JR; Perez-Perez GI; Rice TW; Blaser MJ; Richter JE. "CagA-positive strains of Helicobacter pylori may protect against Barrett's esophagus". American journal of gastroenterology. 2000; 95: 2206 (#J0020884)
93. Yanez P; la Garza AM; Perez-Perez G; Cabrera L; Munoz O; Torres J. "Comparison of invasive and noninvasive methods for the diagnosis and evaluation of eradication of Helicobacter pylori infection in children". Archives of medical research (Mexico). 2000; 31: 415 (#J0047806)

All data from NYU School of Medicine Ehrman Medical Library Faculty Bibliography

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Dr. Guillermo Ignacio Perez Perez

 

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