Program Objectives
Specific objectives for the Pediatric Hematology/Oncology rotation are outlined below and are based on recommendations published previously (A.D. Lascari et al Am J Ped Hem Onc. 8: 245-47,1986)
To develop a differential diagnosis and work up for *:
- Anemia
- Neutropenia
- Thrombocytopenia
- Thrombocytosis
- Pancytopenia
- Adenopathy
- Splenomegaly
- Abdominal mass
- Mediastanal mass
- Thrombosis
- Bruising and bleeding
To understand the diagnosis, pathophysiology and management of the following hematological conditions:
- Hemophilia, Von Willebrand disease *
- Vitamin K deficiency *
- Congenital thrombocytopenia
- Platelet function disorders
- Disseminated intravascular coagulation *
- Hemolytic uremic syndrome
- Immune thrombocytopenia, anemia, neutropenia
- Red blood cell membrane defects *
- Hemoglobinopathies *
- Red blood cell enzymes defects
- Transient erytroblastopenia
- Aplastic anemia
To be familiar with the diagnosis, molecular basis and management of the following oncological conditions:
- Pathogenesis of Childhood cancer *
- Acute lymphoblastic leukemia *
- Acute myelogenous leukemia
- Histiocytosis
- Hodgkin's disease
- Non-Hodgkin's lymphoma
- Brain tumors *
- Neuroblastoma
- Renal tumors
- Bone and soft tissue sarcomas
- Retinoblastoma
- Hepatic tumors
To understand the principles of therapy of commonly encountered hematological and oncological conditions*:
- Chemotherapy
- Transfusion therapy, pheresis therapy
- Management of coagulopathy
- Management of sickle cell disease/thalassemia and transfusional hemochromatosis
- Tumor lysis syndrome and other oncological emergencies
- Deep venous thrombosis and pulmonary embolism
- Management of fever and neutropenia
* Special emphasis
